BDBM50540800 CHEMBL4642739

SMILES: CCOCc1cn(nn1)-c1cccc(c1)S(=O)(=O)Nc1ccccc1N1CCOCC1

InChI Key: InChIKey=BRHWJHSCHXXOTK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540800   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540800 (CHEMBL4642739) Show SMILES CCOCc1cn(nn1)-c1cccc(c1)S(=O)(=O)Nc1ccccc1N1CCOCC1 Show InChI InChI=1S/C21H25N5O4S/c1-2-29-16-17-15-26(24-22-17)18-6-5-7-19(14-18)31(27,28)23-20-8-3-4-9-21(20)25-10-12-30-13-11-25/h3-9,14-15,23H,2,10-13,16H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020)
					More data for this Ligand-Target Pair