BDBM50541238 CHEMBL4641181

SMILES: Cl.N[C@H](Cc1ccc(Cl)cc1Cl)C(=O)N1Cc2ccc(N)cc2C1

InChI Key: InChIKey=DPJXEWUGEVOYNX-PKLMIRHRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50541238   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50541238 (CHEMBL4641181) Show SMILES Cl.N[C@H](Cc1ccc(Cl)cc1Cl)C(=O)N1Cc2ccc(N)cc2C1 |r| Show InChI InChI=1S/C17H17Cl2N3O.ClH/c18-13-3-1-10(15(19)7-13)6-16(21)17(23)22-8-11-2-4-14(20)5-12(11)9-22;/h1-5,7,16H,6,8-9,20-21H2;1H/t16-;/m1./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin)				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair