BDBM50541307 CHEMBL4639234

SMILES: CCCSc1nc(=O)cc(O)n1-c1ccccc1OCC

InChI Key: InChIKey=MUABTPGBUZMTGF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50541307   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apelin receptor (Homo sapiens (Human))	BDBM50541307 (CHEMBL4639234) Show SMILES CCCSc1nc(=O)cc(O)n1-c1ccccc1OCC |(39.43,-44.01,;40.77,-44.78,;42.1,-44,;43.43,-44.77,;44.77,-44,;44.77,-42.45,;46.1,-41.68,;46.1,-40.14,;47.44,-42.45,;47.44,-43.99,;48.77,-44.76,;46.1,-44.76,;46.1,-46.29,;44.77,-47.06,;44.77,-48.61,;46.11,-49.38,;47.44,-48.61,;47.44,-47.06,;48.77,-46.28,;50.11,-47.05,;51.44,-46.27,)| Show InChI InChI=1S/C15H18N2O3S/c1-3-9-21-15-16-13(18)10-14(19)17(15)11-7-5-6-8-12(11)20-4-2/h5-8,10,19H,3-4,9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Agonist activity at human APJ expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair