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SMILES: CC(=O)N1CC2(C1)CN(C2)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C

InChI Key: InChIKey=WTWNGNKMMGWPQW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50541793   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))		BDBM50541793
PNG
(CHEMBL4638415)
Show SMILES CC(=O)N1CC2(C1)CN(C2)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C
Show InChI InChI=1S/C22H23ClN4O2/c1-14(28)25-10-22(11-25)12-26(13-22)16-7-17(9-24-8-16)27-20(29)18-5-4-15(23)6-19(18)21(27,2)3/h4-9H,10-13H2,1-3H3
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
PubMed
n/an/a 23n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay

J Med Chem 63: 6876-6897 (2020)

More data for this
Ligand-Target Pair