BDBM50542619 CHEMBL4643019

SMILES: CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2ccccc12

InChI Key: InChIKey=HXYJPFDCOWRCOF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50542619   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542619 (CHEMBL4643019) Show SMILES CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2ccccc12 Show InChI InChI=1S/C22H24N4O3S/c1-30(28,29)12-4-11-24-18(13-16-5-2-3-6-19(16)24)15-25-21-14-23-10-9-20(21)26(22(25)27)17-7-8-17/h2-3,5-6,9-10,13-14,17H,4,7-8,11-12,15H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020)
					More data for this Ligand-Target Pair