BDBM50542624 CHEMBL4639647

SMILES: CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cc(Cl)ccc12

InChI Key: InChIKey=GYYKUBWUADLANT-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50542624   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542624 (CHEMBL4639647) Show SMILES CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cc(Cl)ccc12 Show InChI InChI=1S/C22H23ClN4O3S/c1-31(29,30)10-2-9-25-18(12-15-11-16(23)3-6-19(15)25)14-26-21-13-24-8-7-20(21)27(22(26)28)17-4-5-17/h3,6-8,11-13,17H,2,4-5,9-10,14H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020)
					More data for this Ligand-Target Pair