BDBM50542750 CHEMBL4645628
SMILES: COP(=O)(C(C)C)c1ccc2oc(nc2c1)-c1ccc2ccccc2c1
InChI Key: InChIKey=LXIGZCSQQSQXGJ-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Utrophin (Homo sapiens) | BDBM50542750 (CHEMBL4645628) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 34 | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Modulation of human utrophinA expressed in mouse H2K cells assessed as upregulation of utrophin production after 24 hrs by luciferase reporter gene a... | J Med Chem 63: 7880-7891 (2020) | |||||||||||
More data for this Ligand-Target Pair |