BDBM50542843 CHEMBL4641659
SMILES: CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O
InChI Key: InChIKey=NQJCDDPQQXUUFZ-FSJACQRISA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuropeptide Y receptor type 4 (Homo sapiens (Human)) | BDBM50542843 (CHEMBL4641659) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | PubMed | 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description Displacement of [3H]UR-KK200 from human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ measured after 90 mins by scintillation counting ... | J Med Chem 63: 8198-8215 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptide Y receptor type 4 (Homo sapiens (Human)) | BDBM50542843 (CHEMBL4641659) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | PubMed | 63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description Displacement of [3H]UR-KK200 from human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ measured after 90 mins by scintillation counting ... | J Med Chem 63: 8198-8215 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptide Y receptor type 1 (Homo sapiens (Human)) | BDBM50542843 (CHEMBL4641659) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | PubMed | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description Displacement of [3H]UR-MK299 from Y1 receptor in human SK-N-MC cells | J Med Chem 63: 8198-8215 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptide Y receptor type 1 (Homo sapiens (Human)) | BDBM50542843 (CHEMBL4641659) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | PubMed | <3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description Displacement of [3H]UR-MK299 from Y1 receptor in human SK-N-MC cells | J Med Chem 63: 8198-8215 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptide Y receptor type 4 (Homo sapiens (Human)) | BDBM50542843 (CHEMBL4641659) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 930 | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB2 assessed as induction of beta-arrestin2 recruitment measured for 40 mins... | J Med Chem 63: 8198-8215 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptide Y receptor type 4 (Homo sapiens (Human)) | BDBM50542843 (CHEMBL4641659) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 1.07E+3 | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB1 assessed as induction of beta-arrestin1 recruitment measured for 40 mins... | J Med Chem 63: 8198-8215 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptide Y receptor type 4 (Homo sapiens (Human)) | BDBM50542843 (CHEMBL4641659) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 1.07E+3 | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB1 assessed as induction of beta-arrestin1 recruitment measured for 40 mins... | J Med Chem 63: 8198-8215 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptide Y receptor type 4 (Homo sapiens (Human)) | BDBM50542843 (CHEMBL4641659) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 933 | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB2 assessed as induction of beta-arrestin2 recruitment measured for 40 mins... | J Med Chem 63: 8198-8215 (2020) | |||||||||||
More data for this Ligand-Target Pair |