BDBM50543580 CHEMBL4649259

SMILES: COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)-n3c(C)ccc3CN3CCOCC3)c3ccccc3)C(=O)Nc2c1

InChI Key: InChIKey=WWQLGPMYEWKUPS-KTMFPKCZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50543580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
VHL/PDGFRB (Homo sapiens (Human))	BDBM50543580 (CHEMBL4649259) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)-n3c(C)ccc3CN3CCOCC3)c3ccccc3)C(=O)Nc2c1 Show InChI InChI=1S/C33H32N4O4/c1-22-8-12-27(21-36-16-18-41-19-17-36)37(22)26-13-10-25(11-14-26)34-31(23-6-4-3-5-7-23)30-28-15-9-24(33(39)40-2)20-29(28)35-32(30)38/h3-15,20,34H,16-19,21H2,1-2H3,(H,35,38)/b31-30-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-fused human PDGFRbeta cytoplasmic domain (557 to 1106 (end) residues) expressed in baculovirus expression system using F...				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50543580 (CHEMBL4649259) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)-n3c(C)ccc3CN3CCOCC3)c3ccccc3)C(=O)Nc2c1 Show InChI InChI=1S/C33H32N4O4/c1-22-8-12-27(21-36-16-18-41-19-17-36)37(22)26-13-10-25(11-14-26)34-31(23-6-4-3-5-7-23)30-28-15-9-24(33(39)40-2)20-29(28)35-32(30)38/h3-15,20,34H,16-19,21H2,1-2H3,(H,35,38)/b31-30-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of N-terminal GST fused human VEGFR2 cytoplasmic domain (790 to 1356 (end) residues) expressed in baculovirus expression system using FAM-...				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair