BDBM50543603 CHEMBL4648577

SMILES: CN(C)CCCCCSC1=Nc2ccccc2C(CC(=O)NCc2ccc(F)cc2)N1c1ccc(cc1)-c1ccc(F)cc1

InChI Key: InChIKey=MGJWWKFNLMFMAB-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50543603   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50543603 (CHEMBL4648577) Show SMILES CN(C)CCCCCSC1=Nc2ccccc2C(CC(=O)NCc2ccc(F)cc2)N1c1ccc(cc1)-c1ccc(F)cc1 |t:9| Show InChI InChI=1S/C36H38F2N4OS/c1-41(2)22-6-3-7-23-44-36-40-33-9-5-4-8-32(33)34(24-35(43)39-25-26-10-16-29(37)17-11-26)42(36)31-20-14-28(15-21-31)27-12-18-30(38)19-13-27/h4-5,8-21,34H,3,6-7,22-25H2,1-2H3,(H,39,43)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of human Cav3.3 expressed in tsA-201 cells by patch clamp electrophysiology				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50543603 (CHEMBL4648577) Show SMILES CN(C)CCCCCSC1=Nc2ccccc2C(CC(=O)NCc2ccc(F)cc2)N1c1ccc(cc1)-c1ccc(F)cc1 |t:9| Show InChI InChI=1S/C36H38F2N4OS/c1-41(2)22-6-3-7-23-44-36-40-33-9-5-4-8-32(33)34(24-35(43)39-25-26-10-16-29(37)17-11-26)42(36)31-20-14-28(15-21-31)27-12-18-30(38)19-13-27/h4-5,8-21,34H,3,6-7,22-25H2,1-2H3,(H,39,43)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of human Cav3.1 expressed in tsA-201 cells by patch clamp electrophysiology				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair
Voltage-gated calcium channel (Homo sapiens (Human))	BDBM50543603 (CHEMBL4648577) Show SMILES CN(C)CCCCCSC1=Nc2ccccc2C(CC(=O)NCc2ccc(F)cc2)N1c1ccc(cc1)-c1ccc(F)cc1 |t:9| Show InChI InChI=1S/C36H38F2N4OS/c1-41(2)22-6-3-7-23-44-36-40-33-9-5-4-8-32(33)34(24-35(43)39-25-26-10-16-29(37)17-11-26)42(36)31-20-14-28(15-21-31)27-12-18-30(38)19-13-27/h4-5,8-21,34H,3,6-7,22-25H2,1-2H3,(H,39,43)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	2.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of human Cav3.2 expressed in tsA-201 cells by patch clamp electrophysiology				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair