BDBM50543604 CHEMBL4642220

SMILES: Fc1ccc(CNC(=O)CC2N(C(SCCCCCN3CCCC3)=Nc3ccccc23)c2ccc(cc2)-c2ccc(F)cc2)cc1

InChI Key: InChIKey=YTQJUUBQSXZMTL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50543604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50543604 (CHEMBL4642220) Show SMILES Fc1ccc(CNC(=O)CC2N(C(SCCCCCN3CCCC3)=Nc3ccccc23)c2ccc(cc2)-c2ccc(F)cc2)cc1 |c:24| Show InChI InChI=1S/C38H40F2N4OS/c39-31-16-10-28(11-17-31)27-41-37(45)26-36-34-8-2-3-9-35(34)42-38(46-25-7-1-4-22-43-23-5-6-24-43)44(36)33-20-14-30(15-21-33)29-12-18-32(40)19-13-29/h2-3,8-21,36H,1,4-7,22-27H2,(H,41,45)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of human Cav3.3 expressed in tsA-201 cells by patch clamp electrophysiology				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50543604 (CHEMBL4642220) Show SMILES Fc1ccc(CNC(=O)CC2N(C(SCCCCCN3CCCC3)=Nc3ccccc23)c2ccc(cc2)-c2ccc(F)cc2)cc1 |c:24| Show InChI InChI=1S/C38H40F2N4OS/c39-31-16-10-28(11-17-31)27-41-37(45)26-36-34-8-2-3-9-35(34)42-38(46-25-7-1-4-22-43-23-5-6-24-43)44(36)33-20-14-30(15-21-33)29-12-18-32(40)19-13-29/h2-3,8-21,36H,1,4-7,22-27H2,(H,41,45)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of human Cav3.1 expressed in tsA-201 cells by patch clamp electrophysiology				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair
Voltage-gated calcium channel (Homo sapiens (Human))	BDBM50543604 (CHEMBL4642220) Show SMILES Fc1ccc(CNC(=O)CC2N(C(SCCCCCN3CCCC3)=Nc3ccccc23)c2ccc(cc2)-c2ccc(F)cc2)cc1 |c:24| Show InChI InChI=1S/C38H40F2N4OS/c39-31-16-10-28(11-17-31)27-41-37(45)26-36-34-8-2-3-9-35(34)42-38(46-25-7-1-4-22-43-23-5-6-24-43)44(36)33-20-14-30(15-21-33)29-12-18-32(40)19-13-29/h2-3,8-21,36H,1,4-7,22-27H2,(H,41,45)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	4.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of human Cav3.2 expressed in tsA-201 cells by patch clamp electrophysiology				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair