BDBM50543611 CHEMBL4645813

SMILES: CN(C)CCCCCSC1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccccc1

InChI Key: InChIKey=AVURAPCJQDDGMZ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50543611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50543611 (CHEMBL4645813) Show SMILES CN(C)CCCCCSC1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccccc1 |t:9| Show InChI InChI=1S/C30H36N4OS/c1-33(2)20-12-5-13-21-36-30-32-27-19-11-10-18-26(27)28(34(30)25-16-8-4-9-17-25)22-29(35)31-23-24-14-6-3-7-15-24/h3-4,6-11,14-19,28H,5,12-13,20-23H2,1-2H3,(H,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of human Cav3.3 expressed in tsA-201 cells by patch clamp electrophysiology				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50543611 (CHEMBL4645813) Show SMILES CN(C)CCCCCSC1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccccc1 |t:9| Show InChI InChI=1S/C30H36N4OS/c1-33(2)20-12-5-13-21-36-30-32-27-19-11-10-18-26(27)28(34(30)25-16-8-4-9-17-25)22-29(35)31-23-24-14-6-3-7-15-24/h3-4,6-11,14-19,28H,5,12-13,20-23H2,1-2H3,(H,31,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of human Cav3.1 expressed in tsA-201 cells by patch clamp electrophysiology				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair
Voltage-gated calcium channel (Homo sapiens (Human))	BDBM50543611 (CHEMBL4645813) Show SMILES CN(C)CCCCCSC1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccccc1 |t:9| Show InChI InChI=1S/C30H36N4OS/c1-33(2)20-12-5-13-21-36-30-32-27-19-11-10-18-26(27)28(34(30)25-16-8-4-9-17-25)22-29(35)31-23-24-14-6-3-7-15-24/h3-4,6-11,14-19,28H,5,12-13,20-23H2,1-2H3,(H,31,35)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of human Cav3.2 expressed in tsA-201 cells by patch clamp electrophysiology				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair