BDBM50543785 CHEMBL4646769

SMILES: C[C@@H](Oc1cncc(c1)-c1cnn(c1)C1CCN(CC2CC2)CC1)c1c(Cl)ccc(F)c1Cl

InChI Key: InChIKey=UEAWIPJHMFVRCQ-MRXNPFEDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50543785   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50543785 (CHEMBL4646769) Show SMILES C[C@@H](Oc1cncc(c1)-c1cnn(c1)C1CCN(CC2CC2)CC1)c1c(Cl)ccc(F)c1Cl |r| Show InChI InChI=1S/C25H27Cl2FN4O/c1-16(24-22(26)4-5-23(28)25(24)27)33-21-10-18(11-29-13-21)19-12-30-32(15-19)20-6-8-31(9-7-20)14-17-2-3-17/h4-5,10-13,15-17,20H,2-3,6-9,14H2,1H3/t16-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Sungkyunkwan University Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) by ADP-Glo kinase assay				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair