BDBM50543792 CHEMBL4636429

SMILES: C[C@@H](Oc1ccc2ncc(nc2c1)-c1cnn(CCO)c1)c1c(Cl)ccc(F)c1Cl

InChI Key: InChIKey=SMEURDMIUJBTAL-GFCCVEGCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50543792   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50543792 (CHEMBL4636429) Show SMILES C[C@@H](Oc1ccc2ncc(nc2c1)-c1cnn(CCO)c1)c1c(Cl)ccc(F)c1Cl |r| Show InChI InChI=1S/C21H17Cl2FN4O2/c1-12(20-15(22)3-4-16(24)21(20)23)30-14-2-5-17-18(8-14)27-19(10-25-17)13-9-26-28(11-13)6-7-29/h2-5,8-12,29H,6-7H2,1H3/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Sungkyunkwan University Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) by ADP-Glo kinase assay				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair