BDBM50544701 CHEMBL4632746
SMILES: Clc1ccc(CNC(=O)[C@@H]2C\C(=C/N3CCOCC3)C(=O)N2)c(Cl)c1
InChI Key: InChIKey=KEODEZBMFGQVDQ-PABFRNLHSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50544701![]() (CHEMBL4632746) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 9.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille Curated by ChEMBL | Assay Description Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ... | J Med Chem 63: 2074-2094 (2020) | |||||||||||
More data for this Ligand-Target Pair |