BDBM50544788 CHEMBL4636795
SMILES: CN(C)C(=O)c1ccc(Nc2cc(ccn2)N2CC[C@@](C#N)(C3CC3)C2=O)nc1
InChI Key: InChIKey=CFHPNFDEUWSEIR-OAQYLSRUSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM50544788 (CHEMBL4636795) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Inhibition of TYK2 (unknown origin) | Bioorg Med Chem Lett 30: (2020) | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |