BDBM50544794 CHEMBL4633342

SMILES: CN([C@@H]1CCC[C@@H](C1)C(=O)Nc1c(C)ncn1CC#N)C(=O)c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=SSBZIXQQXRYQNX-MAUKXSAKSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50544794   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50544794 (CHEMBL4633342) Show SMILES CN([C@@H]1CCC[C@@H](C1)C(=O)Nc1c(C)ncn1CC#N)C(=O)c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C22H24F3N5O2/c1-14-19(30(10-9-26)13-27-14)28-20(31)15-5-4-8-18(12-15)29(2)21(32)16-6-3-7-17(11-16)22(23,24)25/h3,6-7,11,13,15,18H,4-5,8,10,12H2,1-2H3,(H,28,31)/t15-,18+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
Lilly China Research and Development Center (LCRDC) Curated by ChEMBL					Assay Description Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair