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BDBM50544801 CHEMBL4647456

SMILES: CN([C@@H]1CCC[C@@H](C1)c1nnc([nH]1)-c1c(C)ncn1C)C(=O)c1cccc(Cl)c1

InChI Key: InChIKey=KLHYDNVEAJQGOW-WMLDXEAASA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50544801   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50544801
PNG
(CHEMBL4647456)
Show SMILES CN([C@@H]1CCC[C@@H](C1)c1nnc([nH]1)-c1c(C)ncn1C)C(=O)c1cccc(Cl)c1 |r|
Show InChI InChI=1S/C21H25ClN6O/c1-13-18(27(2)12-23-13)20-24-19(25-26-20)14-6-5-9-17(11-14)28(3)21(29)15-7-4-8-16(22)10-15/h4,7-8,10,12,14,17H,5-6,9,11H2,1-3H3,(H,24,25,26)/t14-,17+/m0/s1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PubMed
n/an/an/an/a 14n/an/an/an/a



Lilly China Research and Development Center (LCRDC)

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...

Bioorg Med Chem Lett 30: (2020)

More data for this
Ligand-Target Pair