BDBM50545331 CHEMBL4646949
SMILES: Cc1ccc(cc1)-n1nc(C(=O)Nc2ccc(Oc3ccnc(c3)C(=O)NCCCN3CCOCC3)cc2)c(C)cc1=O
InChI Key: InChIKey=LSBYIKINAMFNSD-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50545331![]() (CHEMBL4646949) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangxi Science & Technology Normal University Curated by ChEMBL | Assay Description Inhibition of cMET (unknown origin) using FAM-labeled peptide as substrate pre-incubated for 5 to 10 mins followed by substrate addition and measured... | Bioorg Med Chem Lett 30: (2020) | |||||||||||
More data for this Ligand-Target Pair |