BDBM50545334 CHEMBL4642495

SMILES: Cc1cc(=O)n(nc1C(=O)Nc1ccc(Oc2ccnc(c2)C(=O)NCCCN2CCOCC2)cc1)-c1ccc(Br)cc1F

InChI Key: InChIKey=FMTZKAHIIKXZJN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50545334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50545334 (CHEMBL4642495) Show SMILES Cc1cc(=O)n(nc1C(=O)Nc1ccc(Oc2ccnc(c2)C(=O)NCCCN2CCOCC2)cc1)-c1ccc(Br)cc1F Show InChI InChI=1S/C31H30BrFN6O5/c1-20-17-28(40)39(27-8-3-21(32)18-25(27)33)37-29(20)31(42)36-22-4-6-23(7-5-22)44-24-9-11-34-26(19-24)30(41)35-10-2-12-38-13-15-43-16-14-38/h3-9,11,17-19H,2,10,12-16H2,1H3,(H,35,41)(H,36,42)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of cMET (unknown origin) using FAM-labeled peptide as substrate pre-incubated for 5 to 10 mins followed by substrate addition and measured...				Bioorg Med Chem Lett 30: (2020)
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