BDBM50545570 CHEMBL4633186

SMILES: Fc1ccc(cn1)-c1cc(ccc1[C@H]1CCc2cc(ccc12)S(=O)(=O)Nc1ncccn1)C(F)(F)F

InChI Key: InChIKey=JNAUIFVEKVIDOY-FQEVSTJZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50545570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50545570 (CHEMBL4633186) Show SMILES Fc1ccc(cn1)-c1cc(ccc1[C@H]1CCc2cc(ccc12)S(=O)(=O)Nc1ncccn1)C(F)(F)F |r| Show InChI InChI=1S/C25H18F4N4O2S/c26-23-9-3-16(14-32-23)22-13-17(25(27,28)29)4-7-21(22)20-6-2-15-12-18(5-8-19(15)20)36(34,35)33-24-30-10-1-11-31-24/h1,3-5,7-14,20H,2,6H2,(H,30,31,33)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Lupin Ltd. Curated by ChEMBL					Assay Description Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...				J Med Chem 63: 6107-6133 (2020)
					More data for this Ligand-Target Pair