BDBM50545756 CHEMBL4643066

SMILES: CCOC(=O)CN1CCCC(C1)C1CN(C1)c1cnc2c(C)nn([C@H](C)c3ccc(Cl)cc3Cl)c2n1

InChI Key: InChIKey=WPHCFDWCZLDIEM-QNSVNVJESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50545756   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50545756 (CHEMBL4643066) Show SMILES CCOC(=O)CN1CCCC(C1)C1CN(C1)c1cnc2c(C)nn([C@H](C)c3ccc(Cl)cc3Cl)c2n1 |r| Show InChI InChI=1S/C26H32Cl2N6O2/c1-4-36-24(35)15-32-9-5-6-18(12-32)19-13-33(14-19)23-11-29-25-16(2)31-34(26(25)30-23)17(3)21-8-7-20(27)10-22(21)28/h7-8,10-11,17-19H,4-6,9,12-15H2,1-3H3/t17-,18?/m1/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	596	n/a	n/a	n/a	n/a	n/a	n/a
RAPT Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human CCR4 expressed in rat chem-5 cells assessed as inhibition of CCL22-induced calcium flux measured at 2.5 secs time interv...				J Med Chem 63: 8584-8607 (2020)
					More data for this Ligand-Target Pair