BDBM50545761 CHEMBL4633920

SMILES: C[C@H](c1ccc(Cl)cc1Cl)n1nc(C)c2ncc(nc12)N1CC(C1)[C@H]1CCCN(CCS(C)(=O)=O)C1

InChI Key: InChIKey=OLALRJMAUPJFKD-MSOLQXFVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50545761 (CHEMBL4633920) Show SMILES C[C@H](c1ccc(Cl)cc1Cl)n1nc(C)c2ncc(nc12)N1CC(C1)[C@H]1CCCN(CCS(C)(=O)=O)C1 |r| Show InChI InChI=1S/C25H32Cl2N6O2S/c1-16-24-25(33(30-16)17(2)21-7-6-20(26)11-22(21)27)29-23(12-28-24)32-14-19(15-32)18-5-4-8-31(13-18)9-10-36(3,34)35/h6-7,11-12,17-19H,4-5,8-10,13-15H2,1-3H3/t17-,18+/m1/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	575	n/a	n/a	n/a	n/a	n/a	n/a
RAPT Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at CCR4 in human CCRF-CEM cells assessed as inhibition of CCL22-mediated chemotaxis preincubated for 30 mins followed by CCL22 ad...				J Med Chem 63: 8584-8607 (2020)
					More data for this Ligand-Target Pair
C-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50545761 (CHEMBL4633920) Show SMILES C[C@H](c1ccc(Cl)cc1Cl)n1nc(C)c2ncc(nc12)N1CC(C1)[C@H]1CCCN(CCS(C)(=O)=O)C1 |r| Show InChI InChI=1S/C25H32Cl2N6O2S/c1-16-24-25(33(30-16)17(2)21-7-6-20(26)11-22(21)27)29-23(12-28-24)32-14-19(15-32)18-5-4-8-31(13-18)9-10-36(3,34)35/h6-7,11-12,17-19H,4-5,8-10,13-15H2,1-3H3/t17-,18+/m1/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
RAPT Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human CCR4 expressed in rat chem-5 cells assessed as inhibition of CCL22-induced calcium flux measured at 2.5 secs time interv...				J Med Chem 63: 8584-8607 (2020)
					More data for this Ligand-Target Pair