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SMILES: Cc1noc(C)c1-c1ccc2nc(nc(N3CCOC[C@H]3c3ccccc3)c2c1)-c1cnn(CC(C)(C)O)c1

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50545911   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50545911
PNG
(CHEMBL4750652)
Show SMILES Cc1noc(C)c1-c1ccc2nc(nc(N3CCOC[C@H]3c3ccccc3)c2c1)-c1cnn(CC(C)(C)O)c1 |r|
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 260n/an/an/an/an/a


TBA

Assay Description
Competitive binding affinity to human partial length BRD4 (BD1,2) (N44 to E460 residues) expressed in bacterial expression system by BROMOscan assay

Citation and Details

Article DOI: 10.1016/j.bmcl.2019.03.014
BindingDB Entry DOI: 10.7270/Q2FT8QMQ
More data for this
Ligand-Target Pair