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SMILES: COc1ncc(cc1NS(C)(=O)=O)-c1ccc2ncnc(Nc3cnn(CCO)c3)c2c1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50546013   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50546013
PNG
(CHEMBL4745877)
Show SMILES COc1ncc(cc1NS(C)(=O)=O)-c1ccc2ncnc(Nc3cnn(CCO)c3)c2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.52E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of EGFR (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins followed by substrate addition and measured after 1 ...

Citation and Details

Article DOI: 10.1016/j.bmc.2019.04.024
BindingDB Entry DOI: 10.7270/Q2T1577B
More data for this
Ligand-Target Pair