null

SMILES: CN(CCN(C)C(=O)c1coc2ccccc2c1=O)C(=O)c1cn(-c2cccc(c2)[N+]([O-])=O)c2ccccc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547333   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tumor necrosis factor ligand superfamily member 11 (Homo sapiens)	BDBM50547333 (CHEMBL3742191) Show SMILES CN(CCN(C)C(=O)c1coc2ccccc2c1=O)C(=O)c1cn(-c2cccc(c2)[N+]([O-])=O)c2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.18E+3	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01316 BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11 (Homo sapiens)	BDBM50547333 (CHEMBL3742191) Show SMILES CN(CCN(C)C(=O)c1coc2ccccc2c1=O)C(=O)c1cn(-c2cccc(c2)[N+]([O-])=O)c2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01316 BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
					More data for this Ligand-Target Pair