BindingDB logo
myBDB logout

null

SMILES: CN(CCN(C)S(=O)(=O)c1ccccc1)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1cccc(c1)[N+]([O-])=O

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50547336   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547336
PNG
(CHEMBL4745590)
Show SMILES CN(CCN(C)S(=O)(=O)c1ccccc1)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1cccc(c1)[N+]([O-])=O
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.70E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair