null
SMILES: O=C(N1CCN(CC1)C(=O)c1coc2ccccc2c1=O)c1cn(c2ccccc12)S(=O)(=O)c1ccccc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tumor necrosis factor ligand superfamily member 11 (Homo sapiens) | BDBM50547351![]() (CHEMBL3740702) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01316 BindingDB Entry DOI: 10.7270/Q2PZ5DDQ | |||||||||||
More data for this Ligand-Target Pair |