null

SMILES: CCCc1nn(-c2nc3NC(=O)C(C)(C)c3c(N)n2)c2ccc(Cl)cc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547431   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Guanylate cyclase soluble subunit alpha-1/beta-1 (Homo sapiens (Human))	BDBM50547431 (CHEMBL4778917) Show SMILES CCCc1nn(-c2nc3NC(=O)C(C)(C)c3c(N)n2)c2ccc(Cl)cc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.46E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assay				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127574 BindingDB Entry DOI: 10.7270/Q2XG9VRF
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50547431 (CHEMBL4778917) Show SMILES CCCc1nn(-c2nc3NC(=O)C(C)(C)c3c(N)n2)c2ccc(Cl)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127574 BindingDB Entry DOI: 10.7270/Q2XG9VRF
					More data for this Ligand-Target Pair