null

SMILES: O[C@@H]1CNC(=O)[C@H]1NC(=O)CCc1c([nH]c2c(cc(F)cc12)C#N)-c1ccc(F)cc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50547877   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apolipoprotein L1 (Homo sapiens)	BDBM50547877 (CHEMBL4795347 | US20230271945, Compound 42) Show SMILES O[C@@H]1CNC(=O)[C@H]1NC(=O)CCc1c([nH]c2c(cc(F)cc12)C#N)-c1ccc(F)cc1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent									US Patent US9725441 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2MXG
					More data for this Ligand-Target Pair
Apolipoprotein L1 (Homo sapiens)	BDBM50547877 (CHEMBL4795347 | US20230271945, Compound 42) Show SMILES O[C@@H]1CNC(=O)[C@H]1NC(=O)CCc1c([nH]c2c(cc(F)cc12)C#N)-c1ccc(F)cc1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of APOL1 (unknown origin) in HEK293 cells assessed as thallium influx incubated for 30 mins by FLIPR based thallium influx assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00531 BindingDB Entry DOI: 10.7270/Q25Q50QQ
					More data for this Ligand-Target Pair
Apolipoprotein L1 (Homo sapiens)	BDBM50547877 (CHEMBL4795347 | US20230271945, Compound 42) Show SMILES O[C@@H]1CNC(=O)[C@H]1NC(=O)CCc1c([nH]c2c(cc(F)cc12)C#N)-c1ccc(F)cc1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent									US Patent US9725441 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2MXG
					More data for this Ligand-Target Pair