null
SMILES: O[C@@H]1CNC(=O)[C@H]1NC(=O)CCc1c([nH]c2c(F)cccc12)-c1ccccc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Apolipoprotein L1 (Homo sapiens) | BDBM50547878 (CHEMBL4752052) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of APOL1 (unknown origin) in HEK293 cells assessed as thallium influx incubated for 30 mins by FLIPR based thallium influx assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00531 BindingDB Entry DOI: 10.7270/Q25Q50QQ | |||||||||||
More data for this Ligand-Target Pair |