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SMILES: CNC(=O)c1cnccc1Nc1ccc(Cl)cc1F

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50548118   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Oxidized purine nucleoside triphosphate hydrolase [42-197]


(Homo sapiens)		BDBM50548118
PNG
(CHEMBL4758926)
Show SMILES CNC(=O)c1cnccc1Nc1ccc(Cl)cc1F
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n/an/a 9n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.5b01760
BindingDB Entry DOI: 10.7270/Q2TB1BHR
More data for this
Ligand-Target Pair