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Enter Data

null

SMILES: CN1CC2(CCN(CCc3ccccc3)CC2)OCC1=O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50548590
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50548590 (CHEMBL4754601) Show SMILES CN1CC2(CCN(CCc3ccccc3)CC2)OCC1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	282	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of 3H](+)-pentazocine from human sigma1 receptor expressed in HEK293 cell membranes incubated for 120 mins by liquid scintillation count...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01127 BindingDB Entry DOI: 10.7270/Q2PC35ZC
TBA					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50548590 (CHEMBL4754601) Show SMILES CN1CC2(CCN(CCc3ccccc3)CC2)OCC1=O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-DAMGO from human MOR expressed in CHOK1 cell membranes incubated for 60 mins by liquid scintillation counting method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01127 BindingDB Entry DOI: 10.7270/Q2PC35ZC
TBA					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50548590 (CHEMBL4754601) Show SMILES CN1CC2(CCN(CCc3ccccc3)CC2)OCC1=O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human MOR expressed in CHOK1 cells assessed as stimulation of cAMP accumulation incubated for 45 mins by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01127 BindingDB Entry DOI: 10.7270/Q2PC35ZC
TBA					More data for this Ligand-Target Pair