null
SMILES: COc1cccc(c1)-c1ccc(cc1)-n1cc(nn1)-c1cccc(c1)C(O)=O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calcium release-activated calcium channel protein/Stromal interaction molecule 1 (Homo sapiens (Human)) | BDBM50549363 (CHEMBL4751678) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 807 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium response | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01305 BindingDB Entry DOI: 10.7270/Q2HH6PPZ | |||||||||||
More data for this Ligand-Target Pair |