null

SMILES: Nc1nn2c(N)c(C#N)c(nc2c1\N=N\c1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50551118   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50551118 (CHEMBL4741017) Show SMILES Nc1nn2c(N)c(C#N)c(nc2c1\N=N\c1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50551118 (CHEMBL4741017) Show SMILES Nc1nn2c(N)c(C#N)c(nc2c1\N=N\c1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50551118 (CHEMBL4741017) Show SMILES Nc1nn2c(N)c(C#N)c(nc2c1\N=N\c1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	496	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50551118 (CHEMBL4741017) Show SMILES Nc1nn2c(N)c(C#N)c(nc2c1\N=N\c1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X
					More data for this Ligand-Target Pair
Cyclin-T1/Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM50551118 (CHEMBL4741017) Show SMILES Nc1nn2c(N)c(C#N)c(nc2c1\N=N\c1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50551118 (CHEMBL4741017) Show SMILES Nc1nn2c(N)c(C#N)c(nc2c1\N=N\c1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X
					More data for this Ligand-Target Pair