Search and Browse
Download
Enter Data
null
SMILES: CC\C(=C(\c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCCCNC(=O)\C=C\c2ccc(cc2)C(=C(/CC)c2ccccc2)\c2ccc(O)cc2)cc1)c1ccccc1
InChI Key:
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Estrogen receptor (Homo sapiens (Human)) | BDBM50551586 (CHEMBL4755319) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assay | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112191 BindingDB Entry DOI: 10.7270/Q22R3W9R | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor beta (Homo sapiens (Human)) | BDBM50551586 (CHEMBL4755319) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 256 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at ERbeta (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation measured after 21 h... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112191 BindingDB Entry DOI: 10.7270/Q22R3W9R | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor (Homo sapiens (Human)) | BDBM50551586 (CHEMBL4755319) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at ERalpha (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation measured after 21 ... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112191 BindingDB Entry DOI: 10.7270/Q22R3W9R | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor beta (Homo sapiens (Human)) | BDBM50551586 (CHEMBL4755319) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERbeta by LanthaScreen TR-FRET assay | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112191 BindingDB Entry DOI: 10.7270/Q22R3W9R | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
