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SMILES: Cl.OC[C@H]1CCCN1Cc1ccc(Oc2ccc(cc2)-c2cccc(c2)C(F)(F)F)cc1

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552500   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sphingosine kinase 2


(Homo sapiens (Human))		BDBM50552500
PNG
(CHEMBL4743459)
Show SMILES Cl.OC[C@H]1CCCN1Cc1ccc(Oc2ccc(cc2)-c2cccc(c2)C(F)(F)F)cc1 |r|
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 488n/an/an/an/a


TBA

Assay Description
Inhibition of human SphK2 expressed in Saccharomyces cerevisiae KYA1 assessed as yeast growth at 30 degreeC measured after 24 to 48 hrs

Citation and Details

Article DOI: 10.1016/j.bmc.2020.115941
BindingDB Entry DOI: 10.7270/Q23B63ST
More data for this
Ligand-Target Pair
Sphingosine kinase 1


(Homo sapiens (Human))		BDBM50552500
PNG
(CHEMBL4743459)
Show SMILES Cl.OC[C@H]1CCCN1Cc1ccc(Oc2ccc(cc2)-c2cccc(c2)C(F)(F)F)cc1 |r|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 299n/an/an/an/a


TBA

Assay Description
Inhibition of human SphK1 expressed in Saccharomyces cerevisiae KYA1 assessed as yeast growth at 30 degreeC measured after 24 to 48 hrs

Citation and Details

Article DOI: 10.1016/j.bmc.2020.115941
BindingDB Entry DOI: 10.7270/Q23B63ST
More data for this
Ligand-Target Pair