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SMILES: Cc1ccccc1N1C(=O)\C(S\C1=N/C1CC(F)(F)C1)=C\c1ccc(O)c(Cl)c1

InChI Key:

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50553295   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))		BDBM50553295
PNG
(CHEMBL4758919)
Show SMILES Cc1ccccc1N1C(=O)\C(S\C1=N/C1CC(F)(F)C1)=C\c1ccc(O)c(Cl)c1
PDB

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n/an/a 200n/an/an/an/an/an/a


TBA

Assay Description
Immunomodulatory activity at human S1PR1 expressed in CHO-K1 EDG1 beta-arrestin cells assessed as stimulation of beta-arrestin recruitment incubated ...

Citation and Details

Article DOI: 10.1021/acsmedchemlett.8b00616
BindingDB Entry DOI: 10.7270/Q20868ZH
More data for this
Ligand-Target Pair