null
SMILES: Fc1cccc(CNc2cccc(n2)-c2cc(NC(=O)[C@H]3CNCCO3)ncc2Cl)c1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-T1/Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM50553498 (CHEMBL4782011) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | <8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of His-tagged human CDK9/cyclin T1 expressed in insect cells using biotinylated-cdk7tide peptide incubated for 5 hrs by Alpha Screen assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00744 BindingDB Entry DOI: 10.7270/Q2FB56K3 | |||||||||||
More data for this Ligand-Target Pair |