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SMILES: O[C@H]1CN(c2ccccc2)S(=O)(=O)[C@@]11CCN(Cc2ccc(Cl)cc2)C1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50554788   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dedicator of cytokinesis protein 5


(Homo sapiens)		BDBM50554788
PNG
(CHEMBL4744468)
Show SMILES O[C@H]1CN(c2ccccc2)S(=O)(=O)[C@@]11CCN(Cc2ccc(Cl)cc2)C1 |r|
PDB

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KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.60E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of N-terminal GFP tagged human DOCK5 (1212-1642 residues) expressed in HEK293T cells assessed as reduction in exchange activity incubated ...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01201
BindingDB Entry DOI: 10.7270/Q2V40ZVJ
More data for this
Ligand-Target Pair