null
SMILES: OC1CN(C1)C(=O)c1cccc2N(CCc12)c1cc(Cc2cc(F)cc(c2)C(F)(F)F)ncn1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G-protein coupled receptor 52 (Mus musculus) | BDBM50554906![]() (CHEMBL4788591 | US20240059655, Compound PW0940) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | n/a | n/a | 760 | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 52 (Homo sapiens (Human)) | BDBM50554906![]() (CHEMBL4788591 | US20240059655, Compound PW0940) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 760 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human GPR52 expressed in HEK293 cells assessed as increase in cAMP levels incubated for 15 mins by Glosensor cAMP assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01498 BindingDB Entry DOI: 10.7270/Q22N55XV | |||||||||||
More data for this Ligand-Target Pair |