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SMILES: OC(=O)C(F)(F)F.COc1ccc(CC(=O)NC(=N)N[C@H](CCSC)C(=O)Nc2cc(ccc2C)S(N)(=O)=O)cc1OC

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50555216   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cathepsin D


(Homo sapiens (Human))		BDBM50555216
PNG
(CHEMBL4755672)
Show SMILES OC(=O)C(F)(F)F.COc1ccc(CC(=O)NC(=N)N[C@H](CCSC)C(=O)Nc2cc(ccc2C)S(N)(=O)=O)cc1OC |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 127n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human liver Cathepsin D preincubated for 10 mins followed by substrate addition and further incubated for 2 hrs in dark by fluorimetric...

Citation and Details

Article DOI: 10.1016/j.bmc.2020.115879
BindingDB Entry DOI: 10.7270/Q2HQ43KW
More data for this
Ligand-Target Pair