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SMILES: Cc1ccc(cc1)C(=O)Nc1ccc(cc1)C(=O)NO

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50555671   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase 3


(Homo sapiens (Human))
BDBM50555671
PNG
(CHEMBL4757957)
Show SMILES Cc1ccc(cc1)C(=O)Nc1ccc(cc1)C(=O)NO
PDB

NCI pathway
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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 11n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant full length human HDAC3 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112411
BindingDB Entry DOI: 10.7270/Q2JH3QVS
More data for this
Ligand-Target Pair
Histone deacetylase 11


(Homo sapiens (Human))
BDBM50555671
PNG
(CHEMBL4757957)
Show SMILES Cc1ccc(cc1)C(=O)Nc1ccc(cc1)C(=O)NO
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant full length human HDAC11 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Elect...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112411
BindingDB Entry DOI: 10.7270/Q2JH3QVS
More data for this
Ligand-Target Pair
Histone deacetylase 8


(Homo sapiens (Human))
BDBM50555671
PNG
(CHEMBL4757957)
Show SMILES Cc1ccc(cc1)C(=O)Nc1ccc(cc1)C(=O)NO
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 22n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant full length human HDAC8 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112411
BindingDB Entry DOI: 10.7270/Q2JH3QVS
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))
BDBM50555671
PNG
(CHEMBL4757957)
Show SMILES Cc1ccc(cc1)C(=O)Nc1ccc(cc1)C(=O)NO
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.60n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant full length human HDAC6 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112411
BindingDB Entry DOI: 10.7270/Q2JH3QVS
More data for this
Ligand-Target Pair