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SMILES: OS(=O)(=O)c1ccc(NC(=O)c2[nH]c(nc2-c2ccc(cc2)[N+]([O-])=O)-c2ccccc2)cc1

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50556724   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 11


(Homo sapiens (Human))		BDBM50556724
PNG
(CHEMBL4741934)
Show SMILES OS(=O)(=O)c1ccc(NC(=O)c2[nH]c(nc2-c2ccc(cc2)[N+]([O-])=O)-c2ccccc2)cc1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 20 uM DiFMUP by DiFMUP assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01265
BindingDB Entry DOI: 10.7270/Q24171QP
More data for this
Ligand-Target Pair