null
SMILES: COCCN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2c3COCCn3nc2-c2ccncc2)cc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50557479 (CHEMBL4799263) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Louisiana at Monroe Curated by ChEMBL | Assay Description Inhibition of human ALK2 R206H mutant using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assay | Bioorg Med Chem Lett 12: 2743-7 (2002) Article DOI: 10.1016/j.bmcl.2021.127858 BindingDB Entry DOI: 10.7270/Q25M69C9 | |||||||||||
More data for this Ligand-Target Pair |