null

SMILES: Cc1ccc(Nc2nc(\C=C\c3ccccc3)nc3cc(Br)ccc23)cc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557578   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50557578 (CHEMBL4760459) Show SMILES Cc1ccc(Nc2nc(\C=C\c3ccccc3)nc3cc(Br)ccc23)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant COX-2 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00004 BindingDB Entry DOI: 10.7270/Q2MP56Z1
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50557578 (CHEMBL4760459) Show SMILES Cc1ccc(Nc2nc(\C=C\c3ccccc3)nc3cc(Br)ccc23)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00004 BindingDB Entry DOI: 10.7270/Q2MP56Z1
					More data for this Ligand-Target Pair