null
SMILES: [#7]-c1ccc(cc1)-[#6](\[#6]-n1ccnc1)=[#6](/c1ccc(-[#8])cc1)-c1ccc(-[#8])cc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aromatase (Homo sapiens (Human)) | BDBM50558013![]() (CHEMBL4755831) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human aromatase incubated for 30 mins using fluorometric substrate 7-methoxy-4-trifluoromethylcoumarin in presence of NADPH... | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01677 BindingDB Entry DOI: 10.7270/Q2B2800F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (Homo sapiens (Human)) | BDBM50558013![]() (CHEMBL4755831) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 296 | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of ES2 from recombinant human ER-beta incubated for 2 hrs by fluorescence based assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01677 BindingDB Entry DOI: 10.7270/Q2B2800F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50558013![]() (CHEMBL4755831) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of ES2 from recombinant human ER-alpha incubated for 2 hrs by fluorescence based assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01677 BindingDB Entry DOI: 10.7270/Q2B2800F | |||||||||||
More data for this Ligand-Target Pair |