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SMILES: CN1CCN(CCCOc2cccc3nc(Nc4ccc(Cl)c(c4)C(F)(F)F)ccc23)CC1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50558208   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
High affinity nerve growth factor receptor


(Homo sapiens (Human))		BDBM50558208
PNG
(CHEMBL4797203)
Show SMILES CN1CCN(CCCOc2cccc3nc(Nc4ccc(Cl)c(c4)C(F)(F)F)ccc23)CC1
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.52E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant N-terminal His6-tagged human TrkA (440 to end residues) expressed in baculovirus infected Sf21 insect cells

Citation and Details

Article DOI: 10.1016/j.bmcl.2016.05.047
BindingDB Entry DOI: 10.7270/Q2CV4NDD
More data for this
Ligand-Target Pair