null

SMILES: COc1cccc(F)c1-c1cc2n(ncc2cc1C#N)-c1cccc(n1)N1CCN(C)CC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50559632   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human))	BDBM50559632 (CHEMBL4795146) Show SMILES COc1cccc(F)c1-c1cc2n(ncc2cc1C#N)-c1cccc(n1)N1CCN(C)CC1 |(19.09,-7.98,;19.08,-9.52,;17.75,-10.28,;16.42,-9.51,;15.08,-10.28,;15.08,-11.84,;16.42,-12.59,;16.43,-14.13,;17.74,-11.82,;19.07,-12.59,;20.4,-11.82,;21.74,-12.59,;23.2,-12.1,;24.11,-13.34,;23.22,-14.6,;21.75,-14.13,;20.41,-14.91,;19.07,-14.14,;17.74,-14.91,;16.41,-15.67,;23.67,-10.64,;22.63,-9.51,;23.1,-8.05,;24.61,-7.71,;25.64,-8.85,;25.18,-10.32,;27.15,-8.52,;28.18,-9.67,;29.68,-9.35,;30.15,-7.89,;31.66,-7.56,;29.12,-6.74,;27.61,-7.07,)| Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human))	BDBM50559632 (CHEMBL4795146) Show SMILES COc1cccc(F)c1-c1cc2n(ncc2cc1C#N)-c1cccc(n1)N1CCN(C)CC1 |(19.09,-7.98,;19.08,-9.52,;17.75,-10.28,;16.42,-9.51,;15.08,-10.28,;15.08,-11.84,;16.42,-12.59,;16.43,-14.13,;17.74,-11.82,;19.07,-12.59,;20.4,-11.82,;21.74,-12.59,;23.2,-12.1,;24.11,-13.34,;23.22,-14.6,;21.75,-14.13,;20.41,-14.91,;19.07,-14.14,;17.74,-14.91,;16.41,-15.67,;23.67,-10.64,;22.63,-9.51,;23.1,-8.05,;24.61,-7.71,;25.64,-8.85,;25.18,-10.32,;27.15,-8.52,;28.18,-9.67,;29.68,-9.35,;30.15,-7.89,;31.66,-7.56,;29.12,-6.74,;27.61,-7.07,)| Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair