null

SMILES: Fc1c(Br)c(Cl)ccc1Nc1ncnc2cc3OCCOc3cc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50561519   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50561519 (CHEMBL4762453) Show SMILES Fc1c(Br)c(Cl)ccc1Nc1ncnc2cc3OCCOc3cc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild type EGFR in human U87 cells assessed as heparin/human EGF stimulated phosphorylation after 1 hr by immunoblotting analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.9b00599 BindingDB Entry DOI: 10.7270/Q2JD51G9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50561519 (CHEMBL4762453) Show SMILES Fc1c(Br)c(Cl)ccc1Nc1ncnc2cc3OCCOc3cc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant EGFR expressed in baculovirus infected Sf9 insect cells using poly (Glu, Tyr) 4:1 peptide as substrate incubated for ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.9b00599 BindingDB Entry DOI: 10.7270/Q2JD51G9
					More data for this Ligand-Target Pair